In-Silico Computational Screening of Siddha formulations Visha Sura Kudineer and Adathodai Kudineer against RNA dependent RNA polymerase of SARS CoV-2
نویسندگان
چکیده
Background: Siddha Medicine is an important therapeutic option used for treating various respiratory viral infections and has antiviral herbs. Aim: The study aims to perform the In Silico computational studies of Phytoconstituents formulation Visha Sura Kudineer Adathodai which are commonly in treatment fever tract could be effective against novel coronavirus disease. Methods: Autodock program was molecular docking RNA-dependent RNA polymerase (RdRP) (PDB ID: 6NUR). Results: A total 9 compounds were screened, these 4 namely, Andrographolide Anisotine, Apioside, 1-(p-Methoxybenzoyl) aziridine showed high binding affinity RdRp. Conclusion: Based on further experiments clinical trials, formulations COVID-19.
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ژورنال
عنوان ژورنال: International Journal of Ayurvedic Medicine
سال: 2021
ISSN: ['0976-5921']
DOI: https://doi.org/10.47552/ijam.v12i3.2125